Institute of High Performance Computing

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People: Vibrant & Dynamic Culture

People

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Fluid Dynamics (FD)

Dr. LIN Jing

Dr. LIN Jing


Research Interests:

  • Design of efficient antisense oligonucleotides for human disease therapeutics
  • High throughput peptide microarray for the identification of human disease biomarkers

Qualifications:

  • Ph.D., Life Science, University of Nottingham, UK, 2005
  • B.Sc., Biochemistry, Sun Yat-sen University, 1999

Published Journals/ Articles:

Journals

    • Lin J., Bruni F.M., Fu Z., Malone J., Bardina L., Boner A., Gimenez G., Sampson H.A. A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide Microarray immunoassay. Journal of Allergy and Clinical Immunology129(5): 1321-1328 (2012)
    • Ayuso R., S�nchez-Garcia S., Pascal M., Lin J., Grishina G., Fu Z., Ib��ez M.D., Sastre J., Sampson H.A., Is epitope recognition of shrimp allergens useful to predict clinical reactivity?� Clinical and Experimental Allergy 42(2):293-304 (2012)
    • Arima S., Lin J., Pecora V., Tardella L., A Bayesian hierarchical model for identifying epitopes in peptide microarray data. Biostatistics 13(1):101-12 (2012)
    • Goldis M.E., Bardina L., Gimenez G., Lin J., Sampson H.A. Evaluation of Flu Vaccines with Regards to Their Egg Protein Content. Pediatric Allergy and Immunology 22(6), 642-643 (2011)
    • Perez-Gordo M., Lin J., Bardina L., Pastor-Vargas C., Cases B., Vivanco F., Cuesta-Herranz J., Sampson H.A. Epitope mapping of Atlantic salmon major allergen (Sal s 1) by peptide microarray immunoassay. International Archives of Allergy and Immunology 157(1), 31-40 (2011)
    • Severance E.G., Lin J., Sampson H.A., Gimenez G., Dickerson F. B., Halling M., Gressitt K., Haile L., Stallings C. R., Origoni A. E., Dupont D., Yolken R. H.� Dietary antigens, epitope recognition, and immune complex formation in recent onset psychosis and long-term schizophrenia. Schizophrenia Rsearch 126(1-3):43-50 (2011)
    • Lin J., Wang J., Bardina L., Goldis MA, Shreffler W.G., Sampson H.A. Correlation of IgE/IgG4 milk epitopes and IgE antibody affinity with different phenotypes of milk allergy. Journal of Allergy and Clinical Immunology, 125 (3): 695-702 (2010)
    • Vereda A., Andreae D.A., Lin J., Shreffler W.G., Iba�ez M.D., Cuesta-Herranz J., Bardina L., Sampson H.A., Identification of IgE sequential epitopes of lentil (Len c 1) by peptide microarray immunoassay. Journal of Allergy and Clinical Immunology 126(3): 596-601(2010)
    • Ayuso R., S�nchez-Garcia S., Lin J., Fu Z., Ib��ez M.D., Carrillo T., Blanco C., Goldis M., Bardina L., Sastre J., Sampson H.A. Greater epitope recognition of shrimp allergens by children than adults suggests that shrimp sensitization decreases with age. Journal of Allergy and Clinical Immunology 125(6):1286-1293(2010)
    • Savilahti E.M., Rantanen V., Lin J., Karinen S., Saarinen K.M., Goldis M., M�kel� M., Hautaniemi S., Savilahti E., Sampson, H.A. Early recovery from cow’s milk allergy is associated with decreasing IgE and increasing IgG4 binding to cow’s milk epitopes, Journal of Allergy and Clinical Immunology 125(6):1315-1321(2010)
    • Lin J., Sampson H.A. The role of IgE binding epitopes in the characterization of food allergy (Invited Review) Current Opinion in Allergy and Clinical Immunology, 9(4): 357-63 (2009)
    • Lin J., Bardina L., Shreffler W.G. Microarrayed allergen molecules for diagnostics of allergy. Chapter 19 In : Reineke U., ed. Methods in Molecular Biology- Epitope Mapping Protocols. 524: 259-72 (2008)
    • Cerecedo I., Zamora J., Shreffler W.G., Lin J., Bardina L., Dieguez M.C., Wang J., Muriel A., de la Hoz B., Sampson H.A. Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay. Journal of Allergy and Clinical Immunology. 122(3):589-94 (2008)
    • Flinterman A.E., Knol E.F., Andreae D.A., Bardina L., den Hartog Jager C.F., Lin J., Pasmans S.G.M.A., Bruijnzeel-Koomen C.A.F.M., Sampson H.A., Hoffen E., Shreffler W.G. Peanut epitopes for IgE and IgG4 in peanut sensitized children in relation to severity of peanut allergy. Journal of Allergy and Clinical Immunology. 121(3):737-743 (2008)
    • Lin J., Renault N., Haas H., Schramm G., Vieths S., Vogel L., Falcone F.H., Alcocer M.J.C. A novel tool for the detection of allergic sensitisation combining protein microarrays with human basophils. Clinical and� Experimental Allergy 37(12), 1854–62 (2007)
    • Lin J., Shewry P. R., Archer D. B., Beyer K., Niggemann B., Hass H., Wilson P., Alcocer, M.J.C. The potential allergenicity of two 2S albumins from soybean (Glycine max): a protein microarray approach. International Archives of Allergy and Immunology 141(2):91-102 (2006)
    • Lin J., Fido R., Shewry P. R., Archer D.B., Alcocer M.J.C. The expression and processing of two recombinant 2S albumins from soybean (Glycine max) in the yeast Pichia pastoris. Biochimica Et Biophysica Acta-Proteins and Proteomics 1698(2), 203-212 (2004)
    • Alcocer M. J. C., Murtagh G. J., Wilson P., Progias P., Lin J., Archer, D. B. The major human structural IgE epitope of the brazil nut allergen Ber e 1: A chimaeric and protein microarray approach. Journal of Molecular Biology. 343 (3), 759-769 (2004)

Conferences

    • Lin J., Bruni F.M., Fu Z., Malone J., Bardina L., Gimenez G., Boner A., Sampson H.A., “IgE and IgG4 Epitope Mapping by Peptide Microarray Immunoassay for the Identification of Patients with Symptomatic Peanut Allergy” at the American Academy of Allergy Asthma & Immunology Annual Meeting (2011), San Francesco, CA, USA; Journal Of Allergy And Clinical Immunology, 127(2):AB179
    • Lin J., Wang J., Bardina L., Goldis M., Sampson H.A.., “Correlation of IgE affinity with different phenotypes of milk allergy using a competition peptide microarray” at the American Academy of Allergy Asthma & Immunology� Annual Meeting (2010), New Orleans, LA, USA; Journal Of Allergy And Clinical Immunology, 125(2): AB23
    • Lin J., Bardina L., Goldis M., Fu Z., Sampson H.A., “Validation and Upgrading of a Sensitive Peptide Microarray System for Large-scale Epitope Mapping” at the American Academy of Allergy Asthma & Immunology Annual Meeting (2009), Washington D.C., USA; Journal Of Allergy And Clinical Immunology, 123(2): S178
    • Lin J., Bardina L., Bruni F.M., Shreffler W.G., Wang J., Sampson H.A., “Development of a Reliable and Sensitive Peptide Microarray for Large-Scale Epitope Mapping of Milk Allergens.” at the American Academy of Allergy Asthma & Immunology Annual Meeting (2008), Philadelphia, USA; Journal Of Allergy And Clinical Immunology, 121(2): S246
    • Lin J., “Are protein structural features involved in the "intrinsic" allergenicity of 2S albumins? - A protein microarray approach.” at the 9th International Symposium on Immunological, Chemical and Clinical Problems of Food Allergy (2004), Budapest, Hungary

Book Chapter(s)

    • Lin J., Bardina L., Shreffler W.G. Microarrayed allergen molecules for diagnostics of allergy. Chapter 19 In : Reineke U., ed. Methods in Molecular Biology- Epitope Mapping Protocols. 524: 259-72 (2008)
    • Falcone F. H., Lin J., Renault N., Haas H., Schramm G., Gibbs B. F., Alcocer, M.J.C. The Live Basophil Allergen Array (LBAA): a Pilot Study. In Falus, A., ed. Clinical Applications of Immunomics.(Immunomics Reviews), Volume 2 (2008)
    • Lin J., Fu Z., Allergenic characterization of soybean proteins (2007)

Patents

    • Sampson H.A., Lin J., Bardina L., “Methods for characterizing antibody binding affinity and epitope diversity in food allergy”, US patent published in March 2011. Application number 20110071043

This page is last updated at: 30-APR-2013