Institute of High Performance Computing

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People: Vibrant & Dynamic Culture

People

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Computing Science (CS)

Dr. Victor TONG Joo Chuan

Dr. Victor TONG Joo Chuan


Research Interests:

     
  • Data mining
  • Machine-learning 
  • Bioinformatics

Qualifications:

     
  • Ph.D. in Biochemistry - National University of Singapore, Singapore (2007)
  • B.Sc. in Computer Science (Hons) - National University of Singapore, Singapore (2002)

Published Journals/ Articles:

Journals

     

    • Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmuller KH, Renia L, Rotzschke O, Ng LF. (2012) Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein. EMBO Mol Med 4: 330-343.
    • Khan JM, Cheruku HR, Tong JC, Ranganathan S. (2011) MPID-T2: a database for sequence-structure-function analyses of pMHC and TR/pMHC structures. Bioinformatics, 27: 1192-1193.
    • Tong JC, Ng LF. (2011) Understanding infectious agents from an in silico perspective. Drug Discov Today;16:42-49.
    • Bernardo PH, Sivaraman T, Wan KF, Xu J, Krishnamoorthy J, Song CM, Tian L, Chin JS, Lim DS, Mok HY, Yu VC, Tong JC, Chai CL. (2010) Structural insights into the design of small molecule inhibitors that selectively antagonize Mcl-1. J Med Chem;53:2314-2318.
    • Tong JC, Simarmata D, Lin RTP, Renia L, Ng LFP. (2010) HLA class I restriction as a possible driving force for Chikungunya evolution. PLoS ONE;5:e9291.
    • Kam Y-K, Ong EKS, Renia L, Tong JC, Ng LFP. (2009) Immuno-biology of Chikungunya and implications for disease intervention. Microbes Infect;11:1186-1196.
    • Wee LJK, Tong JC, Tan TW, Ranganathan S. (2009) A multi-factor model for caspase degradome prediction. BMC Genomics;10:S6.  
    • Song CM, Lim SJ, Tong JC. (2009) Recent advances in computer-aided drug design. Brief Bioinform;10:579-591.
    • Tong JC, Ren EC. (2009) Immunoinformatics: current trends and future directions. Drug Discov Today;14:684-689.
    • Muh HC, Tong JC, Tammi MT. (2009) AllerHunter: a SVM-pairwise system for assessment of allergenicity and allergic cross-reactivity in proteins. PLoS ONE;4:e5861.
    • Tong JC, Lim SJ, Mun HC, Chew FT, Tammi MT. (2009) Allergen Atlas: a comprehensive knowledge center and analysis resource for allergen information. Bioinformatics;25:979-980.
    • Song CM, Bernardo PH, Chai CLL, Tong JC. (2009) CLEVER: pipeline for designing in silico chemical libraries. J Mol Graph Model;27:578-583.
    • Aung Z, Tong JC. (2008) BSAlign: a rapid graph-based algorithm for detecting ligand-binding sites in protein structures. Genome Inform;21:65-76.
    • Ormsby RJ, Ranganathan S, Tong JC, Griggs KM, Dimasi DP, Hewitt AW, Burdon KP, Craig JE, Hoh J, Gordon DL. (2008) The complement factor H Y402H polymorphism associated with age-related macular degeneration affects interactions with multiple ligands. Invest Opthalmol Vis Sci;49:1763-1770.
    • Tong JC, Tan TW, Ranganathan S. (2007) In silico grouping of peptide/HLA class I complexes using structural interaction characteristics. Bioinformatics;23:177-183.
    • Zhang ZH, Koh JLY, Zhang GL, Tammi MT, Tong JC. (2007) AllerTool: A web server for predicting allergenicity and allergic cross-reactivity. Bioinformatics;23:504-506.
    • Tong JC, Zhang GL, Tan TW, August JT, Brusic V, Ranganathan S. (2006) Prediction of HLA-DQ3.2beta ligands: Evidence of multiple registers in class II binding peptides. Bioinformatics;22:1232-1238.
    • Kong L, Lee BTK, Tong JC, Tan TW, Ranganathan S. (2004) SDPMOD: an automated comparative modeling server for small disulphide-bonded proteins. Nucleic Acids Res;32:W356-W359.

Conferences

     

    • Sheng C, Hsu W, Lee ML, Tong JC, Ng SK. Mining mutation patterns in biological sequences. 28th International Conference on Data Engineering (ICDE), Los Angeles, USA, March 1-6, 2010.
    • Zhang GL, Tong JC, Zhang ZH, Zheng Y, August JT, Kwoh CK, Brusic V. Computational models for identifying promiscuous HLA-B7 binders based on information theory and support vector machine. International Conference on Biomedical and Pharmaceutical Engineering, Singapore, December 11-13, 2006.

Book Chapter(s)

     

    • Tong JC. Computational methods in toxicoepigenomics. (2012) Toxicology and epigenetics. Sahu SC (ed), Wiley.
    • Ranganathan S, Tong JC, Tan TW. (2008) Structural immunoinformatics. Immunoinformatics. Schoenbach C, Ranganathan S, Brusic V (eds), Springer, Immunomics Reviews (vol 1).
    • Tan TW, Tammi M, Choo KH, Tong JC, Bajic V. (2004) Biological databases and web services: metrics for qualitative analysis. Information Processing and Living Systems. World Scientific Publishing Co.

This page is last updated at: 01-MAR-2013